Welcome to the DEBtox information site
Welcome to the DEBtox information page, the
site for people that want to make sense of ecotoxicity data.
This site contains information on mechanistic models for the
analysis of stressor effects on the life-history traits of
individual organisms (and from there to higher and lower
levels of biological organisation). Specifically, this site
is about models based on animal energy budgets (DEBtox and DEBkiss) and survival models
from the GUTS framework.
This website constitues a node in the international DEBnet
network, together with the associated site of DEBtox Research.
The mission of DEBtox.info is to simplify biology to
get to the essence of what toxicants (and other stresses)
are actually doing to organisms. Simplification is necessary
if we need to gain understanding. Furthermore, we cannot
expect to test even a small fraction of all possible
(combinations of) toxicants, species and environmental
conditions. Once we get to the essence, it is possible to
make educated predictions of toxicant effects for untested
chemicals, untested species, and under untested conditions.
Here, you can find information, lists of relevant
publications, (links to) free e-books, and freely
downloadable Matlab packages to analyse your data. Use the
major categories on the top left of the screen to navigate
through this site; the corresponding sub-categories will
appear right next to it in the submenu.
Upcoming courses and events
- In the first part of 2017, there will another round of
the international DEB course, with a tele part
(March-April at your own location) and a hands-on part
(in Tromsø, Norway, 21-30 May). More
- 31 May-2 June. Immediately after the DEB course, there
will be the 5th International DEB Symposium, also in
Tromsø (call for abstracts has opened). More
- 10-13 July 2017. PREDITOX summer school in Lyon,
France. The school aims at helping to improve skills in
modelling (incl. TKTD modelling) and statistical
inference for a better analysis of bioassays. More
- For August 2018, we are planning to organise a new
round of the TKTD modelling summer course DynModTox in Denmark.
- The 2017 edition of the LabexMER post-doctoral
program for young scientists is now opened. The aim of
the program is to give creative young scientists the
opportunity to develop their own research project in one
of the LabexMER laboratories (France). Deadline for
applications: April 15th, 2017. The Brest group of DEB
modelers encourage applications dealing with the
modelling of the effect of multiple stressors on marine
organisms in support of lab experiments. More information.
Older news over here.
- 12 May 2017: Spotted a small error in BYOM when
calculatin the intervals on LC50s with the
likelihood-region method. This corrected in a small update to version 4.01.
- 27-28 April 2017: Release of BYOM 4.0 on the BYOM page. This is a major
update, with many new features, but old scripts and
packages will not work anymore! All packages have been
updated; the two GUTS packages have been combined, and
some have been renamed for clarity. Plus, a new package
has been added to fit classical dose-response curves.
- 16 January 2017: A comprehensive review on DEB theory
by Marko Jusup and co-workers has just appeared on-line
of Life Reviews. The review is accompanied by a
number of commentaries.
- 29 November 2016: New paper from the EnergyBar
project: Jager T et al. (2017). Modelling the
dynamics of growth, development and lipid storage in the
marine copepod Calanus finmarchicus. Marine
Biology 164:1. DOI
10.1007/s00227-016-3030-8 (Open Access!)
- October 2016: The book "Marine Ecotoxicology: current
Knowledge and Future Issues" has just come out. I wrote
a chapter "Dynamic modelling for uptake and effects of
chemicals" in there. The book can obtained from Elsevier
or your favourite bookstore, or via ScienceDirect.
The support page for my chapter can be found over here.